SPECIALIZED PRO-RESOLVING MEDIATORS AS POTENTIAL REGULATORS OF INFLAMMATORY MACROPHAGE RESPONSES IN COVID-19

The recent outbreak of SARS-CoV2 has emerged as one of the biggest pandemics of our century, with outrageous health, social and economic consequences globally.Macrophages may lay in the center of COVID-19 pathogenesis and lethality and treatment of the macrophage-induced cytokine storm has emerged as essential.Specialized pro-resolving mediators (S

AIM: Accumulating evidence suggests that extracellular galectin-1 and galectin-3 promote angiogenesis.Increased expression of galectin-1 and/or galectin-3 has been reported to be associated with tumour progression.Thus, it is critical to identify their influence on angiogenesis.METHODS: We examined the individual and combined effects of galectin-1